The total number of records retrieved from this search are 91. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_619	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	No	Viral strain in combination with radiation, 3 Gy (synergism)	No	Prof. Richard Marais lab	Human melanoma cell line	A375	1.0E+5 cells per well	NA	MTT assay	0.001 MOI	77% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_620	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	No	Viral strain in combination with radiation, 3 Gy (synergism)	No	Prof. Richard Marais lab	Human melanoma cell line	A375	1.0E+5 cells per well	NA	MTT assay	0.01 MOI	77% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_621	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	No	Viral strain in combination with radiation, 3 Gy (synergism)	No	Prof. Richard Marais lab	Human melanoma cell line	A375	1.0E+5 cells per well	NA	MTT assay	0.1 MOI	52% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_622	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	No	Viral strain in combination with radiation, 3 Gy (synergism)	No	Prof. Richard Marais lab	Human melanoma cell line	A375	1.0E+5 cells per well	NA	MTT assay	0.5 MOI	48% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_623	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	No	Viral strain in combination with radiation, 3 Gy (synergism)	No	Prof. Richard Marais lab	Human melanoma cell line	A375	1.0E+5 cells per well	NA	MTT assay	1 MOI	40% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_624	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	No	Viral strain in combination with radiation, 5 Gy (synergism)	No	Prof. Richard Marais lab	Human melanoma cell line	A375	1.0E+5 cells per well	NA	MTT assay	0.001 MOI	60% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_625	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	No	Viral strain in combination with radiation, 5 Gy (synergism)	No	Prof. Richard Marais lab	Human melanoma cell line	A375	1.0E+5 cells per well	NA	MTT assay	0.01 MOI	50% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_626	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	No	Viral strain in combination with radiation, 5 Gy (synergism)	No	Prof. Richard Marais lab	Human melanoma cell line	A375	1.0E+5 cells per well	NA	MTT assay	0.1 MOI	48% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_627	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	No	Viral strain in combination with radiation, 5 Gy (synergism)	No	Prof. Richard Marais lab	Human melanoma cell line	A375	1.0E+5 cells per well	NA	MTT assay	0.5 MOI	40% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_628	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	No	Viral strain in combination with radiation, 5 Gy (synergism)	No	Prof. Richard Marais lab	Human melanoma cell line	A375	1.0E+5 cells per well	NA	MTT assay	1 MOI	38% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_629	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	No	Viral strain in combination with radiation, 3 Gy (antagonism)	No	Prof. Richard Marais lab	Human melanoma cell line	DO4	1.0E+5 cells per well	NA	MTT assay	0.001 MOI	120% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_630	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	No	Viral strain in combination with radiation, 3 Gy (antagonism)	No	Prof. Richard Marais lab	Human melanoma cell line	DO4	1.0E+5 cells per well	NA	MTT assay	0.01 MOI	110% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_631	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	No	Viral strain in combination with radiation, 3 Gy (antagonism)	No	Prof. Richard Marais lab	Human melanoma cell line	DO4	1.0E+5 cells per well	NA	MTT assay	0.1 MOI	60% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_632	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	No	Viral strain in combination with radiation, 3 Gy (antagonism)	No	Prof. Richard Marais lab	Human melanoma cell line	DO4	1.0E+5 cells per well	NA	MTT assay	0.5 MOI	40% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_633	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	No	Viral strain in combination with radiation, 3 Gy (antagonism)	No	Prof. Richard Marais lab	Human melanoma cell line	DO4	1.0E+5 cells per well	NA	MTT assay	1 MOI	30% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_634	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	No	Viral strain in combination with radiation, 5 Gy (antagonism)	No	Prof. Richard Marais lab	Human melanoma cell line	DO4	1.0E+5 cells per well	NA	MTT assay	0.001 MOI	110% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_635	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	No	Viral strain in combination with radiation, 5 Gy (antagonism)	No	Prof. Richard Marais lab	Human melanoma cell line	DO4	1.0E+5 cells per well	NA	MTT assay	0.01 MOI	70% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_636	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	No	Viral strain in combination with radiation, 5 Gy (antagonism)	No	Prof. Richard Marais lab	Human melanoma cell line	DO4	1.0E+5 cells per well	NA	MTT assay	0.1 MOI	58% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_637	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	No	Viral strain in combination with radiation, 5 Gy (antagonism)	No	Prof. Richard Marais lab	Human melanoma cell line	DO4	1.0E+5 cells per well	NA	MTT assay	0.5 MOI	25% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_638	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	No	Viral strain in combination with radiation, 5 Gy (antagonism)	No	Prof. Richard Marais lab	Human melanoma cell line	DO4	1.0E+5 cells per well	NA	MTT assay	1 MOI	25% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_639	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	No	Viral strain in combination with radiation, 3 Gy (synergism)	No	Prof. Richard Marais lab	Human melanoma cell line	MeWo	1.0E+5 cells per well	NA	MTT assay	0.001 MOI	105% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_640	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	No	Viral strain in combination with radiation, 3 Gy (synergism)	No	Prof. Richard Marais lab	Human melanoma cell line	MeWo	1.0E+5 cells per well	NA	MTT assay	0.01 MOI	107% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_641	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	No	Viral strain in combination with radiation, 3 Gy (antagonism)	No	Prof. Richard Marais lab	Human melanoma cell line	MeWo	1.0E+5 cells per well	NA	MTT assay	0.1 MOI	90% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_642	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	No	Viral strain in combination with radiation, 3 Gy (synergism)	No	Prof. Richard Marais lab	Human melanoma cell line	MeWo	1.0E+5 cells per well	NA	MTT assay	0.5 MOI	70% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_643	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	No	Viral strain in combination with radiation, 3 Gy (synergism)	No	Prof. Richard Marais lab	Human melanoma cell line	MeWo	1.0E+5 cells per well	NA	MTT assay	1 MOI	61% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_644	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	No	Viral strain in combination with radiation, 5 Gy (synergism)	No	Prof. Richard Marais lab	Human melanoma cell line	MeWo	1.0E+5 cells per well	NA	MTT assay	0.001 MOI	90% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_645	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	No	Viral strain in combination with radiation, 5 Gy (synergism)	No	Prof. Richard Marais lab	Human melanoma cell line	MeWo	1.0E+5 cells per well	NA	MTT assay	0.01 MOI	93% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_646	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	No	Viral strain in combination with radiation, 5 Gy (antagonism)	No	Prof. Richard Marais lab	Human melanoma cell line	MeWo	1.0E+5 cells per well	NA	MTT assay	0.1 MOI	87% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_647	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	No	Viral strain in combination with radiation, 5 Gy (synergism)	No	Prof. Richard Marais lab	Human melanoma cell line	MeWo	1.0E+5 cells per well	NA	MTT assay	0.5 MOI	58% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_648	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	No	Viral strain in combination with radiation, 5 Gy (synergism)	No	Prof. Richard Marais lab	Human melanoma cell line	MeWo	1.0E+5 cells per well	NA	MTT assay	1 MOI	59% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_679	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	Yes	No	No	Prof. Richard Marais lab	Human melanoma cell line	A375	1.0E+5 cells per well	NA	MTT assay	0.001 MOI	120% cancer cell viability (calculated as relative to mock-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_680	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	Yes	No	No	Prof. Richard Marais lab	Human melanoma cell line	A375	1.0E+5 cells per well	NA	MTT assay	0.01 MOI	105% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_681	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	Yes	No	No	Prof. Richard Marais lab	Human melanoma cell line	A375	1.0E+5 cells per well	NA	MTT assay	0.1 MOI	100% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_682	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	Yes	No	No	Prof. Richard Marais lab	Human melanoma cell line	A375	1.0E+5 cells per well	NA	MTT assay	0.5 MOI	70% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_683	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	Yes	No	No	Prof. Richard Marais lab	Human melanoma cell line	A375	1.0E+5 cells per well	NA	MTT assay	1 MOI	50% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_684	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	Yes	No	No	Prof. Richard Marais lab	Human melanoma cell line	DO4	1.0E+5 cells per well	NA	MTT assay	0.001 MOI	120% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_685	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	Yes	No	No	Prof. Richard Marais lab	Human melanoma cell line	DO4	1.0E+5 cells per well	NA	MTT assay	0.01 MOI	105% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_686	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	Yes	No	No	Prof. Richard Marais lab	Human melanoma cell line	DO4	1.0E+5 cells per well	NA	MTT assay	0.1 MOI	77% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_687	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	Yes	No	No	Prof. Richard Marais lab	Human melanoma cell line	DO4	1.0E+5 cells per well	NA	MTT assay	0.5 MOI	50% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_688	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	Yes	No	No	Prof. Richard Marais lab	Human melanoma cell line	DO4	1.0E+5 cells per well	NA	MTT assay	1 MOI	30% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_689	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	Yes	No	No	Prof. Richard Marais lab	Human melanoma cell line	MeWo	1.0E+5 cells per well	NA	MTT assay	0.001 MOI	120% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_690	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	Yes	No	No	Prof. Richard Marais lab	Human melanoma cell line	MeWo	1.0E+5 cells per well	NA	MTT assay	0.01 MOI	126% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_691	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	Yes	No	No	Prof. Richard Marais lab	Human melanoma cell line	MeWo	1.0E+5 cells per well	NA	MTT assay	0.1 MOI	92% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_692	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	Yes	No	No	Prof. Richard Marais lab	Human melanoma cell line	MeWo	1.0E+5 cells per well	NA	MTT assay	0.5 MOI	72% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_693	Reovirus	RT3D (Reolysin)	RNA	Reoviridae	None	Yes	No	No	Prof. Richard Marais lab	Human melanoma cell line	MeWo	1.0E+5 cells per well	NA	MTT assay	1 MOI	61% cancer cell viability (calculated as relative to non-infected group)	No	No	NA	No response	NA	Down-regulation of the inhibitor of apoptosis (IAP) family of proteins with a corresponding increase in cleaved caspase 9/3	NA	NA	27384486
OV_1437	Adenovirus	ZD-55-IL-18	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-18 gene	Shanghai cell collection	Human melanoma cell line	A375	NA	NA	Crystal violet staining	0.01 MOI	Cell survival observerd	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19498459
OV_1438	Adenovirus	ZD-55-IL-18	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-18 gene	Shanghai cell collection	Human melanoma cell line	A375	NA	NA	Crystal violet staining	0.1 MOI	Cell survival observerd	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19498459
OV_1439	Adenovirus	ZD-55-IL-18	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-18 gene	Shanghai cell collection	Human melanoma cell line	A375	NA	NA	Crystal violet staining	1 MOI	Cell survival observerd	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19498459
OV_1440	Adenovirus	ZD-55-IL-18	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-18 gene	Shanghai cell collection	Human melanoma cell line	A375	NA	NA	Crystal violet staining	10 MOI	100% cell death	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19498459
OV_1441	Adenovirus	ZD-55-IL-18	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-18 gene	Shanghai cell collection	Human melanoma cell line	A375	NA	NA	Crystal violet staining	100 MOI	100% cell death	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19498459
OV_4275	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	SICB	Human melanoma cell line	B16	4000 cells per well	NA	MTT assay	10 pfu	2.19 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347
OV_5092	Vaccinia virus	vvdd-tdTomato-hDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of human DAI	Yes	No	Virus expressing human DAI gene	ATCC	Human melanoma cell line	HS294T	1.0E+4 cells per well	NA	MTS assay	0.001 MOI	70% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5093	Vaccinia virus	vvdd-tdTomato-hDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of human DAI	Yes	No	Virus expressing human DAI gene	ATCC	Human melanoma cell line	HS294T	1.0E+4 cells per well	NA	MTS assay	0.01 MOI	50% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5094	Vaccinia virus	vvdd-tdTomato-hDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of human DAI	Yes	No	Virus expressing human DAI gene	ATCC	Human melanoma cell line	HS294T	1.0E+4 cells per well	NA	MTS assay	0.1 MOI	20% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5095	Vaccinia virus	vvdd-tdTomato-hDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of human DAI	Yes	No	Virus expressing human DAI gene	ATCC	Human melanoma cell line	HS294T	1.0E+4 cells per well	NA	MTS assay	1 MOI	10% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5096	Vaccinia virus	vvdd-tdTomato-mDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of murine DAI	Yes	No	Virus expressing murine DAI gene	ATCC	Human melanoma cell line	HS294T	1.0E+4 cells per well	NA	MTS assay	0.001 MOI	70% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5097	Vaccinia virus	vvdd-tdTomato-mDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of murine DAI	Yes	No	Virus expressing murine DAI gene	ATCC	Human melanoma cell line	HS294T	1.0E+4 cells per well	NA	MTS assay	0.01 MOI	60% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5098	Vaccinia virus	vvdd-tdTomato-mDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of murine DAI	Yes	No	Virus expressing murine DAI gene	ATCC	Human melanoma cell line	HS294T	1.0E+4 cells per well	NA	MTS assay	0.1 MOI	40% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5099	Vaccinia virus	vvdd-tdTomato-mDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of murine DAI	Yes	No	Virus expressing murine DAI gene	ATCC	Human melanoma cell line	HS294T	1.0E+4 cells per well	NA	MTS assay	1 MOI	10% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5100	Vaccinia virus	vvdd-tdTomato-hDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of human DAI	Yes	No	Virus expressing human DAI gene	ATCC	Human melanoma cell line	A2058	1.0E+4 cells per well	NA	MTS assay	0.001 MOI	60% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5101	Vaccinia virus	vvdd-tdTomato-hDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of human DAI	Yes	No	Virus expressing human DAI gene	ATCC	Human melanoma cell line	A2058	1.0E+4 cells per well	NA	MTS assay	0.01 MOI	30% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5102	Vaccinia virus	vvdd-tdTomato-hDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of human DAI	Yes	No	Virus expressing human DAI gene	ATCC	Human melanoma cell line	A2058	1.0E+4 cells per well	NA	MTS assay	0.1 MOI	10% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5103	Vaccinia virus	vvdd-tdTomato-hDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of human DAI	Yes	No	Virus expressing human DAI gene	ATCC	Human melanoma cell line	A2058	1.0E+4 cells per well	NA	MTS assay	1 MOI	100% cell killing	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5104	Vaccinia virus	vvdd-tdTomato-mDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of murine DAI	Yes	No	Virus expressing murine DAI gene	ATCC	Human melanoma cell line	A2058	1.0E+4 cells per well	NA	MTS assay	0.001 MOI	80% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5105	Vaccinia virus	vvdd-tdTomato-mDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of murine DAI	Yes	No	Virus expressing murine DAI gene	ATCC	Human melanoma cell line	A2058	1.0E+4 cells per well	NA	MTS assay	0.01 MOI	30% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5106	Vaccinia virus	vvdd-tdTomato-mDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of murine DAI	Yes	No	Virus expressing murine DAI gene	ATCC	Human melanoma cell line	A2058	1.0E+4 cells per well	NA	MTS assay	0.1 MOI	10% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5107	Vaccinia virus	vvdd-tdTomato-mDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of murine DAI	Yes	No	Virus expressing murine DAI gene	ATCC	Human melanoma cell line	A2058	1.0E+4 cells per well	NA	MTS assay	1 MOI	100% cell killing	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5116	Vaccinia virus	vvdd-tdTomato-hDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of human DAI	Yes	No	Virus expressing human DAI gene	ATCC	Human melanoma cell line	SK-MEL-2	1.0E+4 cells per well	NA	MTS assay	0.001 MOI	60% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5117	Vaccinia virus	vvdd-tdTomato-hDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of human DAI	Yes	No	Virus expressing human DAI gene	ATCC	Human melanoma cell line	SK-MEL-2	1.0E+4 cells per well	NA	MTS assay	0.01 MOI	40% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5118	Vaccinia virus	vvdd-tdTomato-hDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of human DAI	Yes	No	Virus expressing human DAI gene	ATCC	Human melanoma cell line	SK-MEL-2	1.0E+4 cells per well	NA	MTS assay	0.1 MOI	10% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5119	Vaccinia virus	vvdd-tdTomato-hDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of human DAI	Yes	No	Virus expressing human DAI gene	ATCC	Human melanoma cell line	SK-MEL-2	1.0E+4 cells per well	NA	MTS assay	1 MOI	100% cell killing	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5120	Vaccinia virus	vvdd-tdTomato-mDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of murine DAI	Yes	No	Virus expressing murine DAI gene	ATCC	Human melanoma cell line	SK-MEL-2	1.0E+4 cells per well	NA	MTS assay	0.001 MOI	90% cell killing	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5121	Vaccinia virus	vvdd-tdTomato-mDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of murine DAI	Yes	No	Virus expressing murine DAI gene	ATCC	Human melanoma cell line	SK-MEL-2	1.0E+4 cells per well	NA	MTS assay	0.01 MOI	70% cell killing	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5122	Vaccinia virus	vvdd-tdTomato-mDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of murine DAI	Yes	No	Virus expressing murine DAI gene	ATCC	Human melanoma cell line	SK-MEL-2	1.0E+4 cells per well	NA	MTS assay	0.1 MOI	20% cell killing	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5123	Vaccinia virus	vvdd-tdTomato-mDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of murine DAI	Yes	No	Virus expressing murine DAI gene	ATCC	Human melanoma cell line	SK-MEL-2	1.0E+4 cells per well	NA	MTS assay	1 MOI	100% cell killing	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5599	Newcastle disease virus	NDV-MK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human melanoma cell line	SK-MEL-2	80% confluency	NA	MTT assay	8 pfu	50% of cancer cell death occurs	No	No	NA	No response	NA	Induction of apoptosis by virus infection	Induction of IFN-Gamma production	NA	US7470426
OV_5600	Newcastle disease virus	NDV-MK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human melanoma cell line	SKMEL-3	80% confluency	NA	MTT assay	2 pfu	50% of cancer cell death occurs	No	No	NA	No response	NA	Induction of apoptosis by virus infection	Induction of IFN-Gamma production	NA	US7470426
OV_5601	Newcastle disease virus	NDV-MK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human melanoma cell line	SKMEL-5	80% confluency	NA	MTT assay	4 pfu	50% of cancer cell death occurs	No	No	NA	No response	NA	Induction of apoptosis by virus infection	Induction of IFN-Gamma production	NA	US7470426
OV_5602	Newcastle disease virus	NDV-MK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human melanoma cell line	A375	80% confluency	NA	MTT assay	37 pfu	50% of cancer cell death occurs	No	No	NA	No response	NA	Induction of apoptosis by virus infection	Induction of IFN-Gamma production	NA	US7470426
OV_5603	Newcastle disease virus	NDV-MK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human melanoma cell line	MALME-3M	80% confluency	NA	MTT assay	778 pfu	50% of cancer cell death occurs	No	No	NA	No response	NA	Induction of apoptosis by virus infection	Induction of IFN-Gamma production	NA	US7470426
OV_5604	Newcastle disease virus	NDV-MK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human melanoma cell line	HT144	80% confluency	NA	MTT assay	28 pfu	50% of cancer cell death occurs	No	No	NA	No response	NA	Induction of apoptosis by virus infection	Induction of IFN-Gamma production	NA	US7470426
OV_5818	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human melanoma cell line	SK-MEL-2	80% confluency	NA	NA	8 pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578
OV_5819	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human melanoma cell line	SKMEL-3	80% confluency	NA	NA	2 pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578
OV_5820	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human melanoma cell line	SKMEL-5	80% confluency	NA	NA	4 pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578
OV_5821	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human melanoma cell line	A375	80% confluency	NA	NA	37 pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578
OV_5822	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human melanoma cell line	MALME-3M	80% confluency	NA	NA	778 pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578
OV_5823	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human melanoma cell line	HT144	80% confluency	NA	NA	28 pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578
OV_5910	Newcastle disease virus	NDV-B1	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human melanoma cell line	SK MEL-2	5E+5 pfu	NA	LDH release assay	0.1 MOI	100% cell killing observed after 3 days	No	No	NA		NA	NA	Virus induced IFN-gamma production	NA	US10035984
OV_5911	Newcastle disease virus	NDV-B1	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human melanoma cell line	B16-F10	5E+5 pfu	NA	LDH release assay	0.1 MOI	40% cell killing after 3 days	No	No	NA	No response	NA	NA	Virus induced IFN-gamma production	NA	US10035984
OV_5912	Newcastle disease virus	NDV-F3aa	RNA	Paramyxoviridae	Virus expressing NS1 protein	Yes	No	No	ATCC	Human melanoma cell line	SK MEL-2	5E+5 pfu	NA	LDH release assay	0.1 MOI	100% cell killing observed after 3 days	No	No	NA	No response	NA	NA	Virus induced IFN-gamma production	NA	US10035984
OV_5913	Newcastle disease virus	NDV-F3aa	RNA	Paramyxoviridae	Virus expressing NS1 protein	Yes	No	No	ATCC	Human melanoma cell line	B16-F10	5E+5 pfu	NA	LDH release assay	0.1 MOI	30% cell killing after 3 days	No	No	NA	No response	NA	NA	Virus induced IFN-gamma production	NA	US10035984